Enrichment of megabase-sized DNA molecules for single-molecule optical mapping and next-generation sequencing

Next-generation sequencing (NGS) has caused a revolution, yet left a gap: long-range genetic information from native, non-amplified DNA fragments is unavailable. It might be obtained by optical mapping of megabase-sized DNA molecules. Frequently only a specific genomic region is of interest, so here...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Sci Rep
Päätekijät: Łopacińska-Jørgensen, Joanna M., Pedersen, Jonas N., Bak, Mads, Mehrjouy, Mana M., Sørensen, Kristian T., Østergaard, Peter F., Bilenberg, Brian, Kristensen, Anders, Taboryski, Rafael J., Flyvbjerg, Henrik, Marie, Rodolphe, Tommerup, Niels, Silahtaroglu, Asli
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Publishing Group UK 2017
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5738345/
https://ncbi.nlm.nih.gov/pubmed/29263336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-18091-6
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