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Single-molecule compaction of megabase-long chromatin molecules by multivalent cations
To gain insight into the conformational properties and compaction of megabase-long chromatin molecules, we reconstituted chromatin from T4 phage DNA (165 kb) and recombinant human histone octamers (HO). The unimolecular compaction, induced by divalent Mg(2+) or tetravalent spermine(4+) cations, stud...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5778610/ https://ncbi.nlm.nih.gov/pubmed/29145649 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkx1135 |
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