Internal Motion of Chromatin Fibers Is Governed by Dynamics of Uncompressed Linker Strands

Chromatin compaction and internal motion are fundamental aspects of gene expression regulation. Here, we have investigated chromatin fibers comprising recombinant histone octamers reconstituted with double-stranded bacteriophage T4-DNA. The size of the fibers approaches the typical size of genomic t...

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Veröffentlicht in:Biophys J
Hauptverfasser: Basak, Rajib, Rosencrans, William, Yadav, Indresh, Yan, Peiyan, Berezhnoy, Nikolay V., Chen, Qinming, van Kan, Jeroen A., Nordenskiöld, Lars, Zinchenko, Anatoly, van der Maarel, Johan R.C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Biophysical Society 2020
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Articles
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7732777/
https://ncbi.nlm.nih.gov/pubmed/33121944
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.10.018
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