Stabilizing Off-pathway Oligomers by Polyphenol Nanoassemblies for IAPP Aggregation Inhibition

Experimental studies have shown that many naturally occurring polyphenols have inhibitory effect on the aggregation of several proteins. Here, we use discrete molecular dynamics (DMD) simulations and high-throughput dynamic light scattering (DLS) experiments to study the anti-aggregation effects of...

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Vydáno v:Sci Rep
Hlavní autoři: Nedumpully-Govindan, Praveen, Kakinen, Aleksandr, Pilkington, Emily H., Davis, Thomas P., Chun Ke, Pu, Ding, Feng
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2016
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4725907/
https://ncbi.nlm.nih.gov/pubmed/26763863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep19463
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