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Structural variants of yeast prions show conformer-specific requirements for chaperone activity
Molecular chaperones monitor protein homeostasis and defend against the misfolding and aggregation of proteins that is associated with protein conformational disorders. In these diseases, a variety of different aggregate structures can form. These are called prion strains, or variants, in prion dise...
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| Veröffentlicht in: | Mol Microbiol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4725586/ https://ncbi.nlm.nih.gov/pubmed/25060529 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/mmi.12725 |
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