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Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity
Benzoquinone (BQ) and benzoquinone derivatives (BQD) are used in the production of dyes and cosmetics. While BQ, an extreme skin sensitizer, is an electrophile known to covalently modify proteins via Michael Addition (MA) reaction whilst halogen substituted BQD undergo nucleophilic vinylic substitut...
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| Publicado en: | Toxicology |
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| Autores principales: | , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2015
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4724239/ https://ncbi.nlm.nih.gov/pubmed/26612505 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2015.11.002 |
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