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Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity

Benzoquinone (BQ) and benzoquinone derivatives (BQD) are used in the production of dyes and cosmetics. While BQ, an extreme skin sensitizer, is an electrophile known to covalently modify proteins via Michael Addition (MA) reaction whilst halogen substituted BQD undergo nucleophilic vinylic substitut...

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Bibliografske podrobnosti
izdano v:Toxicology
Main Authors: Mbiya, Wilbes, Chipinda, Itai, Simoyi, Reuben H., Siegel, Paul D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724239/
https://ncbi.nlm.nih.gov/pubmed/26612505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2015.11.002
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