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Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers

Chemical allergens bind directly, or after metabolic or abiotic activation, to endogenous proteins to become allergenic. Assessment of this initial binding has been suggested as a target for development of assays to screen chemicals for their allergenic potential. Recently we reported a nitrobenzene...

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Bibliografische gegevens
Gepubliceerd in:Toxicology
Hoofdauteurs: Chipinda, Itai, Mbiya, Wilbes, Adigun, Risikat Ajibola, Morakinyo, Moshood K., Law, Brandon F., Simoyi, Reuben H., Siegel, Paul D.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2013
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593055/
https://ncbi.nlm.nih.gov/pubmed/24333919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.11.009
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