Detailed mechanistic investigation into the S-nitrosation of cysteamine

The nitrosation of cysteamine (H(2)NCH(2)CH(2)SH) to produce cysteamine-S-nitrosothiol (CANO) was studied in slightly acidic medium by using nitrous acid prepared in situ. The stoichiometry of the reaction was H(2)NCH(2)CH(2)SH + HNO(2) → H(2)NCH(2)CH(2)SNO + H(2)O. On prolonged standing, the nitros...

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Detalhes bibliográficos
Publicado no:Can J Chem
Main Authors: Morakinyo, Moshood K., Chipinda, Itai, Hettick, Justin, Siegel, Paul D., Abramson, Jonathan, Strongin, Robert, Martincigh, Bice S., Simoyi, Reuben H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4651662/
https://ncbi.nlm.nih.gov/pubmed/26594054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1139/v2012-051
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