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Substituent Effects on the Reactivity of Benzoquinone Derivatives with Thiols

Benzoquinone (BQ) is an extremely potent electrophilic contact allergen that haptenates endogenous proteins through Michael addition (MA). It is also hypothesized that BQ may haptenate proteins via free radical formation. The objective of this study was to assess the inductive effects (activating an...

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Bibliografiska uppgifter
Huvudupphovsmän: Mbiya, Wilbes, Chipinda, Itai, Siegel, Paul D., Mhike, Morgen, Simoyi, Reuben H.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2012
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644549/
https://ncbi.nlm.nih.gov/pubmed/23237669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300417z
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