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Substituent Effects on the Reactivity of Benzoquinone Derivatives with Thiols

Benzoquinone (BQ) is an extremely potent electrophilic contact allergen that haptenates endogenous proteins through Michael addition (MA). It is also hypothesized that BQ may haptenate proteins via free radical formation. The objective of this study was to assess the inductive effects (activating an...

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Sonraí Bibleagrafaíochta
Main Authors: Mbiya, Wilbes, Chipinda, Itai, Siegel, Paul D., Mhike, Morgen, Simoyi, Reuben H.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2012
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3644549/
https://ncbi.nlm.nih.gov/pubmed/23237669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300417z
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