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Substituent Effects on the Reactivity of Benzoquinone Derivatives with Thiols
Benzoquinone (BQ) is an extremely potent electrophilic contact allergen that haptenates endogenous proteins through Michael addition (MA). It is also hypothesized that BQ may haptenate proteins via free radical formation. The objective of this study was to assess the inductive effects (activating an...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3644549/ https://ncbi.nlm.nih.gov/pubmed/23237669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx300417z |
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