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Pyridoxylamine reactivity kinetics as an amine based nucleophile for screening electrophilic dermal sensitizers

Chemical allergens bind directly, or after metabolic or abiotic activation, to endogenous proteins to become allergenic. Assessment of this initial binding has been suggested as a target for development of assays to screen chemicals for their allergenic potential. Recently we reported a nitrobenzene...

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Detalhes bibliográficos
Publicado no:Toxicology
Main Authors: Chipinda, Itai, Mbiya, Wilbes, Adigun, Risikat Ajibola, Morakinyo, Moshood K., Law, Brandon F., Simoyi, Reuben H., Siegel, Paul D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4593055/
https://ncbi.nlm.nih.gov/pubmed/24333919
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2013.11.009
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