Reactivity measurement in estimation of benzoquinone and benzoquinone derivatives’ allergenicity

Benzoquinone (BQ) and benzoquinone derivatives (BQD) are used in the production of dyes and cosmetics. While BQ, an extreme skin sensitizer, is an electrophile known to covalently modify proteins via Michael Addition (MA) reaction whilst halogen substituted BQD undergo nucleophilic vinylic substitut...

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Bibliografiske detaljer
Udgivet i:Toxicology
Main Authors: Mbiya, Wilbes, Chipinda, Itai, Simoyi, Reuben H., Siegel, Paul D.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724239/
https://ncbi.nlm.nih.gov/pubmed/26612505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tox.2015.11.002
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