Alternative cleavage and polyadenylation in spermatogenesis connects chromatin regulation with post-transcriptional control

BACKGROUND: Most mammalian genes display alternative cleavage and polyadenylation (APA). Previous studies have indicated preferential expression of APA isoforms with short 3’ untranslated regions (3’UTRs) in testes. RESULTS: By deep sequencing of the 3’ end region of poly(A) + transcripts, we report...

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Bibliographic Details
Published in:BMC Biol
Main Authors: Li, Wencheng, Park, Ji Yeon, Zheng, Dinghai, Hoque, Mainul, Yehia, Ghassan, Tian, Bin
Format: Artigo
Language:Inglês
Published: BioMed Central 2016
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4724118/
https://ncbi.nlm.nih.gov/pubmed/26801249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12915-016-0229-6
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