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Signalling scaffolds and local organization of cellular behaviour

Cellular responses to environmental cues involve the mobilization of GTPases, protein kinases and phosphoprotein phosphatases. The spatial organization of these signalling enzymes by scaffold proteins helps to guide the flow of molecular information. Allosteric modulation of scaffolded enzymes can a...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Nat Rev Mol Cell Biol
Main Authors: Langeberg, Lorene K., Scott, John D.
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722875/
https://ncbi.nlm.nih.gov/pubmed/25785716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3966
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