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Signalling scaffolds and local organization of cellular behaviour

Cellular responses to environmental cues involve the mobilization of GTPases, protein kinases and phosphoprotein phosphatases. The spatial organization of these signalling enzymes by scaffold proteins helps to guide the flow of molecular information. Allosteric modulation of scaffolded enzymes can a...

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Detalles Bibliográficos
Publicado en:Nat Rev Mol Cell Biol
Main Authors: Langeberg, Lorene K., Scott, John D.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722875/
https://ncbi.nlm.nih.gov/pubmed/25785716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3966
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