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Signalling scaffolds and local organization of cellular behaviour

Cellular responses to environmental cues involve the mobilization of GTPases, protein kinases and phosphoprotein phosphatases. The spatial organization of these signalling enzymes by scaffold proteins helps to guide the flow of molecular information. Allosteric modulation of scaffolded enzymes can a...

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Foilsithe in:Nat Rev Mol Cell Biol
Main Authors: Langeberg, Lorene K., Scott, John D.
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2015
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722875/
https://ncbi.nlm.nih.gov/pubmed/25785716
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3966
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