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Signalling scaffolds and local organization of cellular behaviour
Cellular responses to environmental cues involve the mobilization of GTPases, protein kinases and phosphoprotein phosphatases. The spatial organization of these signalling enzymes by scaffold proteins helps to guide the flow of molecular information. Allosteric modulation of scaffolded enzymes can a...
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Publicado no: | Nat Rev Mol Cell Biol |
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Main Authors: | , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2015
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722875/ https://ncbi.nlm.nih.gov/pubmed/25785716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3966 |
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