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Plugging PKA into ERK scaffolds
Cancers often arise in part through derangements in protein kinase signaling. A striking example of this is the finding that approximately 30% of human tumors have mutations in Ras or B-Raf, leading to aberrant ERK kinase activation. Kinase signaling networks are often organized by scaffolding and a...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3322337/ https://ncbi.nlm.nih.gov/pubmed/21311231 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.5.14902 |
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