Panoramix enforces piRNA-dependent cotranscriptional silencing

The Piwi-interacting RNA (piRNA) pathway is a small RNA–based innate immune system that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear Piwi protein is required for transcriptional silencing of transposons, though the precise mechanisms by which this occurs are unkn...

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Bibliografiske detaljer
Udgivet i:Science
Main Authors: Yu, Yang, Gu, Jiaqi, Jin, Ying, Luo, Yicheng, Preall, Jonathan B., Ma, Jinbiao, Czech, Benjamin, Hannon, Gregory J.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722808/
https://ncbi.nlm.nih.gov/pubmed/26472911
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0700
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