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Panoramix enforces piRNA-dependent cotranscriptional silencing
The Piwi-interacting RNA (piRNA) pathway is a small RNA–based innate immune system that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear Piwi protein is required for transcriptional silencing of transposons, though the precise mechanisms by which this occurs are unkn...
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| Опубликовано в: : | Science |
|---|---|
| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2015
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722808/ https://ncbi.nlm.nih.gov/pubmed/26472911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0700 |
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