Panoramix enforces piRNA-dependent cotranscriptional silencing

The Piwi-interacting RNA (piRNA) pathway is a small RNA–based innate immune system that defends germ cell genomes against transposons. In Drosophila ovaries, the nuclear Piwi protein is required for transcriptional silencing of transposons, though the precise mechanisms by which this occurs are unkn...

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Bibliographic Details
Published in:	Science
Main Authors:	Yu, Yang, Gu, Jiaqi, Jin, Ying, Luo, Yicheng, Preall, Jonathan B., Ma, Jinbiao, Czech, Benjamin, Hannon, Gregory J.
Format:	Artigo
Language:	Inglês
Published:	2015
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4722808/ https://ncbi.nlm.nih.gov/pubmed/26472911 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.aab0700
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Panoramix enforces piRNA-dependent cotranscriptional silencing

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