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One Loop to Rule Them All: The Ping-Pong Cycle and piRNA-Guided Silencing

The PIWI-interacting RNA (piRNA) pathway is a conserved defense mechanism that protects the genetic information of animal germ cells from the deleterious effects of molecular parasites, such as transposons. Discovered nearly a decade ago, this small RNA silencing system comprises PIWI-clade Argonaut...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Trends Biochem Sci
Main Authors: Czech, Benjamin, Hannon, Gregory J.
Format: Artigo
Jezik:Inglês
Izdano: Elsevier Trends Journals 2016
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4819955/
https://ncbi.nlm.nih.gov/pubmed/26810602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.12.008
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