piRNA-guided co-transcriptional silencing coopts nuclear export factors

The PIWI-interacting RNA (piRNA) pathway is a small RNA-based immune system that controls the expression of transposons and maintains genome integrity in animal gonads. In Drosophila, piRNA-guided silencing is achieved, in part, via co-transcriptional repression of transposons by Piwi. This depends...

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Vydáno v:eLife
Hlavní autoři: Fabry, Martin H, Ciabrelli, Filippo, Munafò, Marzia, Eastwood, Evelyn L, Kneuss, Emma, Falciatori, Ilaria, Falconio, Federica A, Hannon, Gregory J, Czech, Benjamin
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Chromosomes and Gene Expression
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6677536/
https://ncbi.nlm.nih.gov/pubmed/31219034
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.47999
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