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A transcriptome-wide RNAi screen in the Drosophila ovary reveals novel factors of the germline piRNA pathway

The Drosophila piRNA pathway provides an RNA-based immune system that defends the germline genome against selfish genetic elements. Two inter-related branches of the piRNA system exist: somatic cells that support oogenesis only employ Piwi, whereas germ cells utilize a more elaborated pathway center...

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Detalhes bibliográficos
Main Authors: Czech, Benjamin, Preall, Jonathan B., McGinn, Jon, Hannon, Gregory J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3724427/
https://ncbi.nlm.nih.gov/pubmed/23665227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2013.04.007
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