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What Can the Kinetics of Amyloid Fibril Formation Tell about Off-pathway Aggregation?

Some of the most prevalent neurodegenerative diseases are characterized by the accumulation of amyloid fibrils in organs and tissues. Although the pathogenic role of these fibrils has not been completely established, increasing evidence suggests off-pathway aggregation as a source of toxic/detoxicat...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Crespo, Rosa, Villar-Alvarez, Eva, Taboada, Pablo, Rocha, Fernando A., Damas, Ana M., Martins, Pedro M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722475/
https://ncbi.nlm.nih.gov/pubmed/26601940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699348
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