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What Can the Kinetics of Amyloid Fibril Formation Tell about Off-pathway Aggregation?
Some of the most prevalent neurodegenerative diseases are characterized by the accumulation of amyloid fibrils in organs and tissues. Although the pathogenic role of these fibrils has not been completely established, increasing evidence suggests off-pathway aggregation as a source of toxic/detoxicat...
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| Pubblicato in: | J Biol Chem |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Biochemistry and Molecular Biology
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4722475/ https://ncbi.nlm.nih.gov/pubmed/26601940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699348 |
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