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What Can the Kinetics of Amyloid Fibril Formation Tell about Off-pathway Aggregation?

Some of the most prevalent neurodegenerative diseases are characterized by the accumulation of amyloid fibrils in organs and tissues. Although the pathogenic role of these fibrils has not been completely established, increasing evidence suggests off-pathway aggregation as a source of toxic/detoxicat...

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Bibliografski detalji
Izdano u:J Biol Chem
Glavni autori: Crespo, Rosa, Villar-Alvarez, Eva, Taboada, Pablo, Rocha, Fernando A., Damas, Ana M., Martins, Pedro M.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2016
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722475/
https://ncbi.nlm.nih.gov/pubmed/26601940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.699348
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