Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

In this study, we present data indicating a robust and specific domain interaction between the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop (CL1) and nucleotide binding domain 1 (NBD1) that allows ion transport to proceed in a regulated fashion. We used co-precipit...

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Vydáno v:J Biol Chem
Hlavní autoři: Ehrhardt, Annette, Chung, W. Joon, Pyle, Louise C., Wang, Wei, Nowotarski, Krzysztof, Mulvihill, Cory M., Ramjeesingh, Mohabir, Hong, Jeong, Velu, Sadanandan E., Lewis, Hal A., Atwell, Shane, Aller, Steve, Bear, Christine E., Lukacs, Gergely L., Kirk, Kevin L., Sorscher, Eric J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2016
Témata:
Protein Structure and Folding
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722463/
https://ncbi.nlm.nih.gov/pubmed/26627831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704809
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