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Channel Gating Regulation by the Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) First Cytosolic Loop

In this study, we present data indicating a robust and specific domain interaction between the cystic fibrosis transmembrane conductance regulator (CFTR) first cytosolic loop (CL1) and nucleotide binding domain 1 (NBD1) that allows ion transport to proceed in a regulated fashion. We used co-precipit...

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Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Ehrhardt, Annette, Chung, W. Joon, Pyle, Louise C., Wang, Wei, Nowotarski, Krzysztof, Mulvihill, Cory M., Ramjeesingh, Mohabir, Hong, Jeong, Velu, Sadanandan E., Lewis, Hal A., Atwell, Shane, Aller, Steve, Bear, Christine E., Lukacs, Gergely L., Kirk, Kevin L., Sorscher, Eric J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4722463/
https://ncbi.nlm.nih.gov/pubmed/26627831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.704809
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