DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation

Cancer susceptibility genes have been classified into two groups: gatekeepers and caretakers(1). Gatekeepers are genes that control cell proliferation and death, whereas caretakers are DNA repair genes whose inactivation leads to genetic instability. Abrogation of both caretaker and gatekeeper funct...

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Detaylı Bibliyografya
Yayımlandı:Nature
Asıl Yazarlar: Difilippantonio, Michael J., Zhu, Jie, Chen, Hua Tang, Meffre, Eric, Nussenzweig, Michel C., Max, Edward E., Ried, Thomas, Nussenzweig, André
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2000
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4721590/
https://ncbi.nlm.nih.gov/pubmed/10761921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35006670
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