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DNA repair protein Ku80 suppresses chromosomal aberrations and malignant transformation
Cancer susceptibility genes have been classified into two groups: gatekeepers and caretakers(1). Gatekeepers are genes that control cell proliferation and death, whereas caretakers are DNA repair genes whose inactivation leads to genetic instability. Abrogation of both caretaker and gatekeeper funct...
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| Publicado no: | Nature |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2000
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4721590/ https://ncbi.nlm.nih.gov/pubmed/10761921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/35006670 |
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