EAF2 regulates DNA repair through Ku70/Ku80 in the prostate

Androgens are known to protect prostate cancer cells from DNA damage. Recent studies showed regulation of DNA repair genes by androgen receptor signaling in prostate cancers. ELL-associated factor 2 (EAF2) is an androgen-regulated tumor suppressor and its intracellular localization can be modulated...

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Detalles Bibliográficos
Publicado en:Oncogene
Autores principales: Ai, J, Pascal, L E, Wei, L, Zang, Y, Zhou, Y, Yu, X, Gong, Y, Nakajima, S, Nelson, J B, Levine, A S, Lan, L, Wang, Z
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386836/
https://ncbi.nlm.nih.gov/pubmed/27721405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.373
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