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EAF2 regulates DNA repair through Ku70/Ku80 in the prostate

Androgens are known to protect prostate cancer cells from DNA damage. Recent studies showed regulation of DNA repair genes by androgen receptor signaling in prostate cancers. ELL-associated factor 2 (EAF2) is an androgen-regulated tumor suppressor and its intracellular localization can be modulated...

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Bibliografiske detaljer
Udgivet i:Oncogene
Main Authors: Ai, J, Pascal, L E, Wei, L, Zang, Y, Zhou, Y, Yu, X, Gong, Y, Nakajima, S, Nelson, J B, Levine, A S, Lan, L, Wang, Z
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5386836/
https://ncbi.nlm.nih.gov/pubmed/27721405
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2016.373
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