Structural Studies of Chikungunya Virus-Like Particles Complexed with Human Antibodies: Neutralization and Cell-to-Cell Transmission

Chikungunya virus is a positive-stranded RNA alphavirus. Structures of chikungunya virus-like particles in complex with strongly neutralizing antibody Fab fragments (8B10 and 5F10) were determined using cryo-electron microscopy and X-ray crystallography. By fitting the crystallographically determine...

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Vydáno v:J Virol
Hlavní autoři: Porta, Jason, Mangala Prasad, Vidya, Wang, Cheng-I, Akahata, Wataru, Ng, Lisa F. P., Rossmann, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719628/
https://ncbi.nlm.nih.gov/pubmed/26537684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02364-15
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