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Locking and Blocking the Viral Landscape of an Alphavirus with Neutralizing Antibodies

Alphaviruses are serious, sometimes lethal human pathogens that belong to the family Togaviridae. The structures of human Venezuelan equine encephalitis virus (VEEV), an alphavirus, in complex with two strongly neutralizing antibody Fab fragments (F5 and 3B4C-4) have been determined using a combinat...

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Hlavní autoři: Porta, Jason, Jose, Joyce, Roehrig, John T., Blair, Carol D., Kuhn, Richard J., Rossmann, Michael G.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4136364/
https://ncbi.nlm.nih.gov/pubmed/24920796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01286-14
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