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In Vitro-Assembled Alphavirus Core-Like Particles Maintain a Structure Similar to That of Nucleocapsid Cores in Mature Virus

In vitro-assembled core-like particles produced from alphavirus capsid protein and nucleic acid were studied by cryoelectron microscopy. These particles were found to have a diameter of 420 Å with 240 copies of the capsid protein arranged in a T=4 icosahedral surface lattice, similar to the nucleoca...

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Main Authors: Mukhopadhyay, Suchetana, Chipman, Paul R., Hong, Eunmee M., Kuhn, Richard J., Rossmann, Michael G.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2002
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC136650/
https://ncbi.nlm.nih.gov/pubmed/12368355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.76.21.11128-11132.2002
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