In Vitro-Assembled Alphavirus Core-Like Particles Maintain a Structure Similar to That of Nucleocapsid Cores in Mature Virus

In vitro-assembled core-like particles produced from alphavirus capsid protein and nucleic acid were studied by cryoelectron microscopy. These particles were found to have a diameter of 420 Å with 240 copies of the capsid protein arranged in a T=4 icosahedral surface lattice, similar to the nucleoca...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Mukhopadhyay, Suchetana, Chipman, Paul R., Hong, Eunmee M., Kuhn, Richard J., Rossmann, Michael G.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2002
Subjects:	Structure and Assembly
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC136650/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12368355/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.76.21.11128-11132.2002
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