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p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung

The p70 ribosomal S6 kinase (S6K) is a downstream substrate that is phosphorylated and activated by the mammalian target of rapamycin complex and regulates multiple cellular processes associated with fibrogenesis. Recent studies demonstrate that aberrant mTORC1-S6K signaling contributes to various p...

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書目詳細資料
發表在:Am J Physiol Lung Cell Mol Physiol
Main Authors: Madala, Satish K., Thomas, George, Edukulla, Ramakrishna, Davidson, Cynthia, Schmidt, Stephanie, Schehr, Angelica, Hardie, William D.
格式: Artigo
語言:Inglês
出版: American Physiological Society 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719051/
https://ncbi.nlm.nih.gov/pubmed/26566903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00063.2015
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