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p70 ribosomal S6 kinase regulates subpleural fibrosis following transforming growth factor-α expression in the lung
The p70 ribosomal S6 kinase (S6K) is a downstream substrate that is phosphorylated and activated by the mammalian target of rapamycin complex and regulates multiple cellular processes associated with fibrogenesis. Recent studies demonstrate that aberrant mTORC1-S6K signaling contributes to various p...
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| Veröffentlicht in: | Am J Physiol Lung Cell Mol Physiol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Physiological Society
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4719051/ https://ncbi.nlm.nih.gov/pubmed/26566903 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00063.2015 |
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