Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

One of the most common symptoms of Alzheimer's disease (AD) and related tauopathies is memory loss. The exact mechanisms leading to memory loss in tauopathies are not yet known; however, decreased translation due to ribosomal dysfunction has been implicated as a part of this process. Here we us...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
الحاوية / القاعدة:J Neurosci
المؤلفون الرئيسيون: Meier, Shelby, Bell, Michelle, Lyons, Danielle N., Rodriguez-Rivera, Jennifer, Ingram, Alexandria, Fontaine, Sarah N., Mechas, Elizabeth, Chen, Jing, Wolozin, Benjamin, LeVine, Harry, Zhu, Haining, Abisambra, Jose F.
التنسيق: Artigo
اللغة:Inglês
منشور في: Society for Neuroscience 2016
الموضوعات:
Brief Communications
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719006/
https://ncbi.nlm.nih.gov/pubmed/26791227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3029-15.2016
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