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Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

One of the most common symptoms of Alzheimer's disease (AD) and related tauopathies is memory loss. The exact mechanisms leading to memory loss in tauopathies are not yet known; however, decreased translation due to ribosomal dysfunction has been implicated as a part of this process. Here we us...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Meier, Shelby, Bell, Michelle, Lyons, Danielle N., Rodriguez-Rivera, Jennifer, Ingram, Alexandria, Fontaine, Sarah N., Mechas, Elizabeth, Chen, Jing, Wolozin, Benjamin, LeVine, Harry, Zhu, Haining, Abisambra, Jose F.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719006/
https://ncbi.nlm.nih.gov/pubmed/26791227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3029-15.2016
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