Tau drives translational selectivity by interacting with ribosomal proteins

There is a fundamental gap in understanding the consequences of tau–ribosome interactions. Tau oligomers and filaments hinder protein synthesis in vitro, and they associate strongly with ribosomes in vivo. Here, we investigated the consequences of tau interactions with ribosomes in transgenic mice,...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Koren, Shon A., Hamm, Matthew J., Meier, Shelby E., Weiss, Blaine E., Nation, Grant K., Chishti, Emad A., Arango, Juan Pablo, Chen, Jing, Zhu, Haining, Blalock, Eric M., Abisambra, Jose F.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2019
Assuntos:
Original Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6426815/
https://ncbi.nlm.nih.gov/pubmed/30759285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-019-01970-9
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