Pathological Tau Promotes Neuronal Damage by Impairing Ribosomal Function and Decreasing Protein Synthesis

One of the most common symptoms of Alzheimer's disease (AD) and related tauopathies is memory loss. The exact mechanisms leading to memory loss in tauopathies are not yet known; however, decreased translation due to ribosomal dysfunction has been implicated as a part of this process. Here we us...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Meier, Shelby, Bell, Michelle, Lyons, Danielle N., Rodriguez-Rivera, Jennifer, Ingram, Alexandria, Fontaine, Sarah N., Mechas, Elizabeth, Chen, Jing, Wolozin, Benjamin, LeVine, Harry, Zhu, Haining, Abisambra, Jose F.
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2016
Teme:
Brief Communications
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4719006/
https://ncbi.nlm.nih.gov/pubmed/26791227
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3029-15.2016
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