Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition.

We have measured the binding of EcoRI endonuclease to a complete set of purine-base analogue sites, each of which deletes one functional group that forms a hydrogen bond with the endonuclease in the canonical GAATTC complex. For five of six functional group deletions, the observed penalty in binding...

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Bibliographic Details
Main Authors: Lesser, D R, Kurpiewski, M R, Waters, T, Connolly, B A, Jen-Jacobson, L
Format: Artigo
Language:Inglês
Published: 1993
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC47179/
https://ncbi.nlm.nih.gov/pubmed/8356054
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