Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition.

We have measured the binding of EcoRI endonuclease to a complete set of purine-base analogue sites, each of which deletes one functional group that forms a hydrogen bond with the endonuclease in the canonical GAATTC complex. For five of six functional group deletions, the observed penalty in binding...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Lesser, D R, Kurpiewski, M R, Waters, T, Connolly, B A, Jen-Jacobson, L
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1993
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7548
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