Facilitated distortion of the DNA site enhances EcoRI endonuclease-DNA recognition.
We have measured the binding of EcoRI endonuclease to a complete set of purine-base analogue sites, each of which deletes one functional group that forms a hydrogen bond with the endonuclease in the canonical GAATTC complex. For five of six functional group deletions, the observed penalty in binding...
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| Yayımlandı: | Proc Natl Acad Sci U S A |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
National Academy of Sciences
1993
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC47179/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8356054/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.16.7548 |
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