Attenuation of AMPK signaling by ROQUIN promotes T follicular helper cell formation

T follicular helper cells (Tfh) are critical for the longevity and quality of antibody-mediated protection against infection. Yet few signaling pathways have been identified to be unique solely to Tfh development. ROQUIN is a post-transcriptional repressor of T cells, acting through its ROQ domain t...

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Библиографические подробности
Опубликовано в: :eLife
Главные авторы: Ramiscal, Roybel R, Parish, Ian A, Lee-Young, Robert S, Babon, Jeffrey J, Blagih, Julianna, Pratama, Alvin, Martin, Jaime, Hawley, Naomi, Cappello, Jean Y, Nieto, Pablo F, Ellyard, Julia I, Kershaw, Nadia J, Sweet, Rebecca A, Goodnow, Christopher C, Jones, Russell G, Febbraio, Mark A, Vinuesa, Carola G, Athanasopoulos, Vicki
Формат: Artigo
Язык:Inglês
Опубликовано: eLife Sciences Publications, Ltd 2015
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4716841/
https://ncbi.nlm.nih.gov/pubmed/26496200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.08698
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