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Modulation of Roquin function in myeloid cells reduces Mycobacterium tuberculosis induced inflammation

Damaging inflammation is a hallmark of Mycobacterium tuberculosis infection, and understanding how this is regulated is important for the development of new therapies to limit excessive inflammation. The E3 ubiquitin ligase, Roquin, is involved in immune regulation, however its role in immunity to M...

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Detalhes bibliográficos
Publicado no:J Immunol
Main Authors: Nagalingam, Gayathri, Vinuesa, Carola G., Britton, Warwick J, Saunders, Bernadette M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5570526/
https://ncbi.nlm.nih.gov/pubmed/28747346
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1602069
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