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Delta inulin-based adjuvants promote the generation of polyfunctional CD4(+) T cell responses and protection against Mycobacterium tuberculosis infection

There is an urgent need for the rational design of safe and effective vaccines to protect against chronic bacterial pathogens such as Mycobacterium tuberculosis. Advax™ is a novel adjuvant based on delta inulin microparticles that enhances immunity with a minimal inflammatory profile and has entered...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Counoupas, Claudio, Pinto, Rachel, Nagalingam, Gayathri, Britton, Warwick J., Petrovsky, Nikolai, Triccas, James A.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561132/
https://ncbi.nlm.nih.gov/pubmed/28819247
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-09119-y
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