EPHA2 blockade overcomes acquired resistance to EGFR kinase inhibitors in lung cancer

Despite the success of treating EGFR mutant lung cancer patients with EGFR tyrosine kinase inhibitors (TKIs), all patients eventually acquire resistance to these therapies. Although various resistance mechanisms have been described, there are currently no FDA-approved therapies that target alternati...

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Bibliografske podrobnosti
izdano v:Cancer Res
Main Authors: Amato, Katherine R., Wang, Shan, Tan, Li, Hastings, Andrew K., Song, Wenqiang, Lovly, Christine M., Meador, Catherine B., Ye, Fei, Lu, Pengcheng, Balko, Justin M., Colvin, Daniel C., Cates, Justin M., Pao, William, Gray, Nathanael S., Chen, Jin
Format: Artigo
Jezik:Inglês
Izdano: 2016
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Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715957/
https://ncbi.nlm.nih.gov/pubmed/26744526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-15-0717
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