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Extension of a Protein Docking Algorithm to Membranes and Applications to Amyloid Precursor Protein Dimerization

Novel adjustments are introduced to the docking algorithm, DOCK/PIERR, for the purpose of predicting structures of transmembrane protein complexes. Incorporating knowledge about the membrane environment is shown to significantly improve docking accuracy. The extended version of DOCK/PIERR is shown t...

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Detalles Bibliográficos
Publicado en:Proteins
Main Authors: Viswanath, Shruthi, Dominguez, Laura, Foster, Leigh S., Straub, John E., Elber, Ron
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4715591/
https://ncbi.nlm.nih.gov/pubmed/26404856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/prot.24934
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