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Specific binding of tetratricopeptide repeat (TPR) proteins to heat shock protein 70 (Hsp70) and heat shock protein 90 (Hsp90) is regulated by affinity and phosphorylation

The heat shock proteins Hsp70 and Hsp90 require the help of tetratricopeptide repeat (TPR) domain-containing co-chaperones for many of their functions. Each monomer of Hsp70 or Hsp90 can only interact with a single TPR co-chaperone at a time and each member of the TPR co-chaperone family brings dist...

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Detalhes bibliográficos
Publicado no:Biochemistry
Main Authors: Assimon, Victoria A., Southworth, Daniel R., Gestwicki, Jason E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714923/
https://ncbi.nlm.nih.gov/pubmed/26565746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.5b00801
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