Mice with hepcidin-resistant ferroportin accumulate iron in the retina

Because ferroportin (Fpn) is the only known mammalian cellular iron exporter, understanding its localization and regulation within the retina would shed light on the direction of retinal iron flux. The hormone hepcidin may regulate retinal Fpn, as it triggers Fpn degradation in the gut. Immunofluore...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:FASEB J
Autori principali: Theurl, Milan, Song, Delu, Clark, Esther, Sterling, Jacob, Grieco, Steve, Altamura, Sandro, Galy, Bruno, Hentze, Matthias, Muckenthaler, Martina U., Dunaief, Joshua L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Federation of American Societies for Experimental Biology 2015
Soggetti:
Research Communication
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714557/
https://ncbi.nlm.nih.gov/pubmed/26506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-276758
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