Mice with hepcidin-resistant ferroportin accumulate iron in the retina

Because ferroportin (Fpn) is the only known mammalian cellular iron exporter, understanding its localization and regulation within the retina would shed light on the direction of retinal iron flux. The hormone hepcidin may regulate retinal Fpn, as it triggers Fpn degradation in the gut. Immunofluore...

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Detalhes bibliográficos
Publicado no:FASEB J
Main Authors: Theurl, Milan, Song, Delu, Clark, Esther, Sterling, Jacob, Grieco, Steve, Altamura, Sandro, Galy, Bruno, Hentze, Matthias, Muckenthaler, Martina U., Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado em: Federation of American Societies for Experimental Biology 2015
Assuntos:
Research Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714557/
https://ncbi.nlm.nih.gov/pubmed/26506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-276758
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