Mice with hepcidin-resistant ferroportin accumulate iron in the retina

Because ferroportin (Fpn) is the only known mammalian cellular iron exporter, understanding its localization and regulation within the retina would shed light on the direction of retinal iron flux. The hormone hepcidin may regulate retinal Fpn, as it triggers Fpn degradation in the gut. Immunofluore...

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Bibliographic Details
Published in:FASEB J
Main Authors: Theurl, Milan, Song, Delu, Clark, Esther, Sterling, Jacob, Grieco, Steve, Altamura, Sandro, Galy, Bruno, Hentze, Matthias, Muckenthaler, Martina U., Dunaief, Joshua L.
Format: Artigo
Language:Inglês
Published: Federation of American Societies for Experimental Biology 2015
Subjects:
Research Communication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714557/
https://ncbi.nlm.nih.gov/pubmed/26506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-276758
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