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Mice with hepcidin-resistant ferroportin accumulate iron in the retina

Because ferroportin (Fpn) is the only known mammalian cellular iron exporter, understanding its localization and regulation within the retina would shed light on the direction of retinal iron flux. The hormone hepcidin may regulate retinal Fpn, as it triggers Fpn degradation in the gut. Immunofluore...

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Detalles Bibliográficos
Publicado en:FASEB J
Main Authors: Theurl, Milan, Song, Delu, Clark, Esther, Sterling, Jacob, Grieco, Steve, Altamura, Sandro, Galy, Bruno, Hentze, Matthias, Muckenthaler, Martina U., Dunaief, Joshua L.
Formato: Artigo
Idioma:Inglês
Publicado: Federation of American Societies for Experimental Biology 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4714557/
https://ncbi.nlm.nih.gov/pubmed/26506980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.15-276758
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